Sparta Prague menjadi pemuncak klasemen dengan 12 poin. Inter Milan di posisi paling buncit dengan 6 poin.
Hasil Liga Europa, 8 Desember 2016 (dalam kurung menunjukkan posisi klasemen akhir grup):
GRUP G - (Ajax Amsterdam, Celta Vigo, Standard Liege, Panathinaikos)
- Panathinaikos 0-2 Celta Vigo (John Guidetti 4', Fabian Orellana 76'-penalti)
- Standard Liege 1-1 Ajax (Benito Raman 84' ; Anwar El Ghazi 27')
GRUP H (Shakhtar Donetsk, Gent, Braga, Konyaspor)
- Braga 2-4 Shaktar (Nikola Stjiljkovic 43', Nikola Vukcevic 89' ; Sergey Krivtsov 22', 62', Taison 39', 66')
- Konyaspor 0-1 Gent (Kalifa Coulibaly 90')
GRUP I (Schalke 04, FC Krasnodar, Salzburg, Nice)
- Nice 2-1 Krasnodar (Alexi Bosetti 63', Maxime Le Marchand 77' ; Fedor Smolov 51')
- Salzburg 2-0 Schalke (Xavier Schlager 22', Josip Radosevic 90')
GRUP J - Fiorentina, PAOK Thessaloniki, Qarabag FK, Slovan Liberec)
- PAOK 2-0 Slovan (Garry Mendes Rodrigues 29', Dimitrios Pelkas 67')
- Qarabag 1-2 Fiorentina (Reynaldo 73' ; Matias Vecino 60', Federico Chiesa 76')
GRUP K - (Sparta Prague, Hapoel Beer-Sheva, Southampton, Inter Milan)
- Inter 2-1 Sparta (Eder 23', 90' ; Lukas Marecek 54')
- Southampton 1-1 Hapoel Beer-Sheva (Virgil van Dijk 90' Maor Bar Buzaglo 79')
GRUP L - (Osmanlispor FK, Villarreal, FC Zuerich, Steaua Bucuresti)
- Osmanlispor 2-0 Zuerich (Dzon Delarge 73', Erdal Klicarslan 89')
- Villarreal 2-1 Steaua (Nicola Sansone 16', Manuel Trigueros 88' ; Vlad Achim 55')